Natural VS Synthetic
Hallucinations VS Disassociations

Natural Psychedelics

These substances are derived from plants, fungi, or animals, and have been used for centuries in traditional rituals and healing practices.

  • Psilocybin Mushrooms: Found in hundreds of mushroom species worldwide; used in ancient ceremonies and modern clinical studies.
  • Mescaline: Naturally occurring in cacti like peyote and San Pedro; used in Native American rituals.
  • Ayahuasca: A brew made from Amazonian plants containing DMT and MAO inhibitors, used by indigenous Amazonian communities.
  • Ibogaine: Extracted from the root bark of the African iboga plant, used in spiritual and healing ceremonies.
  • DMT (from plants like Mimosa hostilis and Psychotria viridis): The active compound in ayahuasca and other traditional preparations.

Synthetic Psychedelics

These are man-made substances, often created in labs for research, recreational, or therapeutic use.

  • LSD (Lysergic Acid Diethylamide): Synthesized in the 20th century from ergot fungus, known for profound, long-lasting effects.
  • MDMA (3,4-Methylenedioxymethamphetamine): Originally developed as a compound for potential therapeutic use, now widely studied for PTSD treatment.
  • 2C-B, DOM, and other synthetic phenethylamines/tryptamines: Created by chemists, these compounds vary in potency and effect.
  • Synthetic DMT and analogs: While DMT occurs naturally, it can also be produced synthetically for research or recreational use.